Aparato Locomotor

VOL 5. Nº1 ENERO/MARZO 2007

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Epidural scar formation in presence of two dural sealants: Duraseal® and Tissucol®. An experimental study

Unidad de Investigación en Neurociencias de la

FUNDACIÓN MAPFRE, Cátedra FUNDACION

MAPFRE-UAM de Investigación en Daño Cerebral

Hospital Universitario Puerta de Hierro. Madrid

Aranda M.A.

Zurita M.

Aguayo C.

Bonilla C.

Vaquero J.

Objective: To study epidural scar induced by the presence of Duraseal® and Tissucol® after laminectomy.

Methods: 15 Wistar rats were used to perform a D6-D8 laminectomy with dural exposure. In control groups no sealants were used after laminectomy and in the other two groups Duraseal® and Tissucol® were used, respectivetly. Three months after laminectomy, the width of the scar was measured in each goup, and compared.

Results: No statistical differences were found in the width of the epidural scar produced by Duraseal® when compared to controls or Tissucol®.

Conclusions: Duraseal® and Tissucol® can be used in space epidural space after a laminectomy, without the epidural scarring increases.

Correspondencia:

J. Vaquero.
Servicio de Neurocirugía,
Hospital Universitario
Puerta de Hierro, San Martín de Porres,
4. 28035-Madrid.
E-mail: jvaqueroc@telefonica.net

Patología del Aparato Locomotor, 2007; 5 (1): 40-45


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