Aparato Locomotor

VOL.18 Nº3, JULIO/SEPTIEMBRE 2007

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Risk factors of target organ damage caused by hypertension

Álvarez Aliaga A., Rodríguez Blanco L.H.,
Fonseca Aguilera A.A., Fonseca Muñoz J.C.,
López Costa C., Hernández Galano M.E.

Hospital Provincial Universitario
Carlos Manuel de Céspedes.
Santiago de Cuba. Bayamo. Cuba.

A case–control study was carried out at «Carlos Manuel de Céspedes» teaching hospital of Bayamo, Granma from January 1st, 2004 to December 31st, 2005 in patients with a diagnosis of hypertension selected off at random 1:2 (100 cases/200 controls). The aim of the study was to identify and quantify the incidence of hypertension risk factors on the onset of target organ damage. Hypertensive heart diseases were the predominant target organ damage (36, 15%). Male patients had a twofold risk of lesion (OR 2,52; CI 1,45-4,44; p 0,000). The over-65-year-age group had a risk increase of eleven times compared to younger ages (OR 11, 23; CI 6, 10-20, 82; p 0,000). Heavy smoking also increased the risk (OR 3, 76; CI 1, 32- 10, 99; p 0,004). Sedentarism was premorbid factor more closely related to organ damage (OR 9, 67; CI 5, 23-17, 99; p 0,000). Non-controlled patients showed a twofold risk of organic lesion (OR 2, 40; CI 1, 41- 4, 09; p 0,005). A longer time after the onset of disease exhibited a sexfold risk increase (31-40: OR 6, 06; CI 3, 05-12, 14; p 0,000). Severity of the condition showed a greater relation organic damage (OR 4, 64; CI 2, 53-8, 52; p 0,000). The study concluded with a logistic regression analysis that showed independent risk factors being the most outstanding over see male patients are greater risk and the time after the onset of the condition.

Correspondencia:

A. Álvarez Aliaga
Armando Barrero 10 alto. Pedro Pompa.
Bayamo Granma. Cuba
dochcmc.grm@infomed.sld.cu

MAPFRE MEDICINA, 2007; 18 (3): 190-200


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