MAPFRE MEDICINA

VOL.18 Nº3, JULIO/SEPTIEMBRE 2007

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Correlation between 6-minute walking test and transthoracic echocardiography for diagnosing chronic thromboembolic pulmonary hypertension

Jiménez D.1, Escobar C.2, Martí D.2 ,
Díaz G.3, Sueiro A.1

1 Servicio de Neumología, Hospital Ramón y Cajal. Madrid
2 Unidad de Ecocardiografía. Servicio de Cardiología, Hospital Ramón y Cajal. Madrid
3 Servicio de Neumología. Hospital La Zarzuela. Madrid

Purpose: To determine the diagnostic yield of the 6-minute walking test (6MWT) to predict chronic thromboembolic pulmonary hypertension (CTPH) in a cohort of patients with acute pulmonary embolism (PE).

Methods: The study population included consecutive patients with confirmed diagnosis of acute symptomatic PE. All patients underwent transthoracic echocardiography and 6MWT 4 weeks after diagnosis. The correlation between the distance walked in the 6MWT and the echocardiographic findings was analized.

Results: Of the 86 study patients, 19% had a diagnosis of pulmonary hypertension, defined by a systolic pulmonary pressure equal or greater than 30 mm Hg. With a predefined cut-off point of 300 hundred metres, the negative predictive value of the 6MWT for CPTH was 93% (95% CI, 85-100). The negative likelihood ratio was 0.3 (95% CI, 0.1-1). There was a significant correlation between the systolic pulmonary pressure measured by transthoracic echocardiography and the distance walked in the 6MWT (r = 0.79; P < 0.001).

Conclusions: There is a significant correlation between the systolic pulmonary pressure measured by transthoracic echocardiography and the distance walked in the 6MWT.

Correspondencia:

D. Jiménez Castro
Servicio de Neumología. Hospital Ramón y Cajal
Dpto. de Medicina. Universidad de Alcalá de Henares. 28034 Madrid
djc_69_98@yahoo.com

MAPFRE MEDICINA, 2007; 18 (3): 154-158


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